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Yes. Past the age of around 21-22, with every year that passes, it becomes much harder for a woman to conceive, and much harder to carry a child to term without miscarrying. Birth defects of every kind become more and more common with each year that passes after around the age of 23, too, from Down's to spina bifida to the 'tism. When a girl is born her ovaries contain all the egg cells she'll ever have, and with each passing year they deteriorate. They have a freshness date.
Women who get pregnant at nineteen tend to carry and give birth without difficulty. "Career women" who wait until they're pushing menopause to try to have children are mutant factories. It is fortunate that they don't succeed very often in getting pregnant in the first place, and, from a certain perspective, it is a mercy that they miscarry so much. This is an ugly and unpleasant thing to contemplate, but it is the truth.
Also, I declare by worldbuilding fiat that anthro women are not subject to this, because it's depressing.
picrel is Averi from the alternate universe where her mom waited until she was fifty-three to decide she wanted to have a kid
instead of chicken sandwiches, she is obsessed with dating sims and over-the-top 1990s Chinese cartoons